Friday, May 11, 2012

Neupogen/Intralipids/Lovenox Cycle #1

Lord have mercy. I think this cycle is a bust.  We jumped the gun and thought I had ovulated, only to realize I ovulated later, so our BD timing was off by about 2-3 days.  Still in the fertile window, but not great timing.  A BFN today on 10DPO, so I think I'm out because I am just not feelin it and my temps have been on the low side since ovulating.

So, here is what I experienced for side effects on this first round:

Intralipids: Nothing other than a bit tired/headachey afterward. The worst part was just sitting there for over 2 hours with the dang needle. Really a breeze overall.

Neupogen: I have felt a bit achey in my joints all cycle long and the day after my first injection I felt some bone aches. Nothing much though, it's practically side-effect free!

Lovenox: I think this gave me some bloating, gas, and a lot of crampy/twingy sensations in my abdomen. The main problem with this drug is injecting it! The med stings like mad during the injection and locally at the site for about 20 minutes afterward, like a burning sensation. It leaves bruises every time at the site, most of them are not too bad, but I have one GIANT bruise the size of an orange on my abdomen. Seriously looks like I was beaten. The other problem is that a few times the injection site leaked, and leaked, and leaked blood...over 15 hours once, right through my clothing at work twice. I contacted the doctor but they just said this was not that uncommon. If it had continued I would have needed to get my platelets checked.  Argh.

So...I'm anxious to get on to a new cycle already. Now I wait for ages for Aunt Flow, who never shows until 17 freakin DPO with my long luteal phases. Had a good cry this morning, I always get so depressed around this time on BFN cycles.  Infertility SUCKS major sour pickles.  

Saturday, May 5, 2012

Affordable Neupogen and Intralipids



I just put this together for the ladies on Fertility Friend on the immunology board by request, so I'm posting it here to for anyone searching! These are sometimes prescribed for women suffering from immune related loss/infertility. I have elevated Natural Killer Cells and alloimmune issues (6 HLA matches with my husband).

Affordable Intralipid Infusions

Prices may vary by region in the US, but the best price I've seen and used was by hiring the Walgreens Infusion Service to come to my home for an Intralipid Infusion: 20% IV, 100 ml, infused over 2 hours. (This was going to cost $300 at a local office with a private doctor.)

As self-pay, I paid:

$80 for Infusion Nurse
$50 for the Intralipids
$15 for Supplies
=$155.00

Affordable Neupogen
Most insurance companies (not all, so check!) will not cover Neupogen for pregnancy. I priced Neupogen from many sources, pharmacies, etc. One of the challenges with Neupogen is that it must be refrigerated/kept cold and cannot be jostled/shaken, which makes ordering it in the mail from outside one's country very difficult.

The best price I found was by purchasing a Walgreens "Prescription Club Membership" for $20 (individuals) or $35 (families) a year. By having that membership, one can save almost $100 a vial on Neupogen as well as many other medications.

At this time, the biggest savings is to purchase the 300mcg/1 ml vial of Neupgoen (not prefilled!!) and not the 480mcg/1.5ml. If you purchase it in bulk, you save a little more money too. 1 vial=$249.99 or in bulk (3+) 1 vial=$246.

My cost as of of May 2012:

4 vials of Neupogen, 300mcg/1ml = $246 a vial ($984 total)
with the Walgreens Prescription Club Membership

Neupogen is prescribed based on body weight, so it will vary a bit based on what you weigh. I am able to get a little more than 5 doses out of each 300mcg/1ml vial. It is taken starting at ovulation, so assuming I take it for 11 days each TTC cycle, it costs $492 in a BFN cycle. In a pregnancy cycle, taking it for a full 30 days, it will cost $1476 per month. It is taken for the first nine weeks, so for a pregnancy it would cost $3444 (in my case).

To me, this is reasonable given the cost of IVIG or LIT as alternatives to Neupogen. IVIG is usually about $3000 per infusion and multiple infusions are generally needed. Getting LIT involves travel to Mexico at this time, so that adds up over several visits.