
One woman's journey to conceive while dealing with recurrent pregnancy loss...the pain, the joy, and the mis-adventures of fertility after age 35.
Wednesday, April 28, 2010
Ultrasounds!

Sunday, April 11, 2010
Beta Purgatory

Levels and slopes were much higher for the remaining 269 women with viable pregnancies with mean levels of 216 mIU/mL on day 16 and 505 mIU/mL on day 18, with an average slope of 140 mIU/mL.
Tuesday, March 30, 2010
My Early Pregnancy Symptoms

2. Speaking of breasts, yesterday morning, before testing, I noticed in the mirror that my Montgomery Tubercles were really showing and more obvious/plentiful. And my nipples were itchy!
3. Shortness of breath during moderate activity. At times it feels like I can't quite take a deep enough breath. This was really noticeable on 9 DPO.
4. This symptom has happened w/every pregnancy: I just feel FAT...clothes don't fit right or look good. I always bloat w/PMS, but this comes on sooner and is a more general feeling.
5. Increased gas...for 4 days in a row now. Horrible! (TMI)
6. A few severe, very quick sharp pains, like round ligament pain, that feels like a charlie horse type cramp in the uterine area. That hit on 6 DPO and made me really wonder, since I only get that in pregnancy. It first hit on 9 DPO on my last BFP cycle.
7. Increased thirst started just yesterday at 10 DPO, which leads to drinking more fluids.
8. Increased fatigue, along w/feeling a bit feverish at times when I get tired.
9. A lot more cervical fluid starting at 4 DPO.
10. Irritable, everything is annoying...like severe PMS but this started at about 7/8 DPO.
11. Sleeplessness: I can't go to sleep at bedtime but then wake early even though I'm tired.
12. Let's talk cramps: At 3 DPO it felt like I was ovulating again through 5 DPO...basic ovulation pains again. At about 6 DPO the cramping felt like a dull, almost burning ache, but all on one side, that continued all day and radiated around the entire area/side. They subsided a bit, off and on, but continued to favor one side for the most part. Yesterday the only thing was a knot feeling just to the right of my belly button (but internally). Today it feels more like a lot of little knot sensations/cramps all over. '
Okay...it's insane I can name this many! Obsessive much?!?
Monday, March 29, 2010
A Very Faint BFP Today

BFP= Big Fat Positive (on a Pregnancy Test)
So, my husband and I were supposed to wait for 2 cycles before trying to concieve again. We really waited only one cycle because he had gone off of his meds in February and we felt we should not lose any time in case he had to go back on them again. (We believe and have been told that his anti-depressants are one of the potential causes for our miscarriages.) Our first cycle trying again was a major disappointment. I seriously thought I might be pregnant at one point and even had a very convincing evaporation line show up on one of the pregancy tests, but alas, it was not to be. I struggled with quite a bit of grief when it was clear I was not pregnant. Additionally, my husband became less sure how much he wanted to keep trying. He also realized (as did I), that he had to get back on his meds. This news spun me into a depression.
By the time we started my next cycle, I realized that this was our "last try" before my husband's meds took their full effect. He went back on them just a few days before I ovulated. We decided to give it a try, not expecting that we would fall pregnant. Additionally, I had started to do some serious soul work around the idea that I may never have another child. To say it has been painful and difficult would be an understatement, especially following our losses.
Sometime after I ovluated, I started having moments of a very strange sort of confidence that I was absolutely, without a doubt, pregnant again. And it was not just that I "felt" pregnant like I had before, but there was a deeper sense: it was simply a fact. I can't explain it, but I didn't like it, in case it was untrue. I also had a very vivid dream that first week after ovulating that I gave birth to a beautiful little boy. It was extremely vivid and wonderful. The only time I have had a dream like that was right before I found out I was pregnant with my daughter.
And then all kinds of "lucky" things seemed to be happening to me related to fertility: a child called me over to hand me a lady bug (they are considered very lucky for pregnancy). I was given 4 different gifts that were butterfly themed (symbol of new life). And while on a walk with my daughter, we found a baby bird's egg, very newly hatched and now empty, lying on the ground at our feet. We took it home. Plus, it's spring and everything seems to be shouting "fertility and new life" as we watch the flowers and leaves budding anew and as we prepare for Easter. It's all about moving out of death into new life and resurrection. Today itself is Holy Monday in the Church calendar and Easter is less than a week away now.
Of course, I had many more moments when I felt tortured by the idea that I could not be pregnant this quickly again, and this might be our last shot. In fact, by yesterday, I had convinced myself that I was simply a complete nut case with all kind of imagined pregnancy symptoms (of which I've had many)! Let's see, my symptoms include: heartburn, fatigue, tender breasts, gas, bloating, irritability, shortness of breath, itchy nipples, increased appetite and thirst, sleeplessness, vivid dreams, cramping and some very painful pulling sensations. The list goes on...seriously. And I kept thinking: what kind of insanity is behind my belief that I'm pregnant?! Of course you're not! Stop that!
So this morning, when I took my Wondfo internet cheapie pregnancy test, I was really and truly not expecting to see anything. But then I could have sworn there was a SUPER faint shadow tint on it...which even faded away when the test dried. Still, I reported the shadow to my Cycle Buddies on Fertility Friend and they were encouraging about it. I felt like I had gone truly mad, obsessing over this shadowy line. But I decided to test again with SMU (second morning urine) and again, another shadowy line, this time just a hair more visible. I took photos, tweaked, and posted them on our fertility discussion board to get opinions. Others could see it and encouraged me to "retest." By 1:30pm, I couldn't stand it. I retested and yet a third shadowy line, this time even more visible, appeared. I finally took my daughter to the store to get some higher quality tests and do some other shopping. We got home and I rushed to the bathroom, having "held it" for a full 5 hours so as not waste the costly tests and get the most accurate result.
I held the test in my hands, as I have so many other countless times, but this time it did not stare back at me stark white. No. It was like magic: a faint but clearly visible second line appeared. On both tests. (The test pictured above is one of them.)
So yes, I do have a very faint BFP only 10 days post ovulation. I have no idea if this pregnancy will last, if this little one will "stick," or if I need to prepare myself for yet another loss. I am less terrified in some ways because I feel prepared for the fact that we are high risk. No longer innocent, I know we could lose this pregnancy in a flash, and it would not be a shock.
We already have an appointment with an RE (Reproductive Endocrinologist) this week. It was to be our first consultation related to fertility, but now I hope it will also be to establish me as a patient who needs some extra attention and support for this pregnancy.
So, I am seeking to take it one day at a time. I don't want to get ahead of myself like I have in the past. I am trying to simply trust God that whatever will be, will be. Truly, the future is not ours! And for now, I'll enjoy those TWO little lines.
Saturday, February 20, 2010
Diagnosing Infertility and the Causes of Miscarriage
Category I: Immunological & Hemotalogical Causes
(blood clotting issues/thrombophilias)
Recurrent miscarriages can sometimes be traced to immunological problems or blood clotting disorders that cause a variety of complications in pregnancy. If you've had several losses, your doctor can (and should) order a blood test panel to check for these types of problems. The tests often include the following:
1. LA- Lupus Anticoagulant (related to the test called dRVVT: Dilute Russell Viper Venom Time)
2. ACA- Anti Cardiolipin Antibodies: molecules that attack cardiolipin causing clotting
3. ANA- Anti-Nuclear Antibodies
4. APA-Antiphospholipid -proteins that cause blood clotting/mc
5. PT and PTTT: Partial Thromboplastin and APTT: Activated Partial Thromboplastin
6. Factor V Leiden-mutation inherited thrombosis
7. Protein C and S levels and activated Protein C activity
8. Prothrombin gene mutation and/antithrombin deficiency - thrombophilia problems
9. Leukocyte Antibody Detection- abnormal attacking of the fetal cells
10. Coagulopathy-defect in clotting causing too much bleeding
11. MTHFR- a mutation that can create problems absorbing Folic Acid (usually treatable w/extra Folic Acid and Vitamin B)- single mutations are not considered problematic but double mutations can be and may elevate Homocystein levels
12. PAI-1 gene mutation: antigen in plasma -causes clotting
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Category II: Ovaries/Egg or Ovarian Reserve Problems
Another potential cause of infertility is a lack of quanity of eggs (low ovarian reserve) or poor quality egg(s) (which can also cause miscarriages), is often due to advanced maternal age. This can happen randomly to young women occasionally too. And as much as I hate the term "advanced maternal age," the risk really is much higher as a woman ages. Problems with a woman's eggs leading to infertility, miscarriage, or other complications rise after age 35. Below are some tests that may uncover any potential problems.
1. Day 3 FSH testing -Follicle stimulating hormone: this tests ovarian reserve (how many eggs are eft and potential egg quality) on Day 3 of a woman's menstrual cycle
2. Estradiol Level testing- similar to FSH, also tests ovarian reserve
3. Day 3 Inhibin- a follow up to low FSH in order to test egg quality
4. Clomiphene Challenge- another follow up to FSH after age 38 (more routine) to check egg quality. Requires taking clomiphene for 5 days.
5. AMH Testing: tests follicles for number of eggs to see if a woman is releasing eggs
6. AOA testing -tests for anti ovarian antibodies that interferes with ovarian funtion
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Category III: Male Sperm Factors
Problems with a man's sperm can certainly lead to infertility or miscarriage, although this is often overlooked and men are often only tested after a woman has been tested thoroughly.
1. Low Sperm count/motility/morphology- not having enough sperm or quality sperm is a rather common problem and can be diagnosed with a basic Sperm Analysis (SA)
2. Sperm DNA fragmentation- caused by environmental or substance damage (smoking, drugs, etc.) and other unknown causes. Of note is the negative impact that some antidepressants (SSRI's) have been shown to have on men's sperm. This type of damage is very problematic, causing infertility and miscarriages, particularly chromosomal problems, and is not diagnosed with a regular sperm analyis...one must get a sperm chromatin test or another test specifically on the DNA of the sperm.
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Category IV: Hormonal Causes
Low or abnormal levels of a number of hormones in women can cause miscarriages and infertility. Below are some of the more frequent hormonally related causes.
1. Hypothyroidism: This can cause problems with ovary function due to hormone stimulations. TSH or the Thyroid Stimulating Hormone test can diagnose this.
2. Low Progesterone: Progesterone is necessary to sustain the uterine lining during pregnancy. Progesterone levels can be checked during pregnancy and supplemented if low. The Day 21 progesterone test is given on Day 21 of a woman's menstrual cycle to ensure that ovulation has taken place (based on progesterone levels).
2. Luteinizing hormone (LH) - LH levels that are too low can prevent ovulation and level too high can indicate chromosomal problems. The LH Test is used to diagnose this.
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Category V: Infections/Viruses
Infections and viruses do not usually cause recurrent losses, but they can be a cause of miscarriage and so I've included them.
1. Toxomplasmosis -diagnosed by the Torch test
2. HIV-test to check for the presence of HIV
3. Hep B and C infections
4. CMV-endocervical infection
5. PARVO- virus (can cause fetal hydrops)
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Category VI: Anatomical Causes
If a woman's fallopian tubes are blocked or abnormal or if a woman's uternus is abnormally shaped or formed, this can cause infertility or miscarriages. Two ways to check a woman's uterus and/or fallopian tubes include:
1.HSG-Hysterosalpingogram (x-ray with dye) or Hysteroscopy (tiny camera): ensures that the fallopian tubes are open and the uterus is normal and no scarring or abnormalites are present
2. Uterine Ultrasound: checks for any uternine abnormalities via a thorough ultrasound
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Category VII: Chromosomal Causes
Sometimes a random accident occurs within either the egg or sperm during the early stages of development causing one extra gene (trisomy) or one less gene (monosomy) to develop in the embryo. Many are lethal to the developing embryo. These are not usually genetic in origin but are due to a random accident or to poor egg or sperm quality. Sometimes one or more parents may have an undiagnosed genetic translocation that causes more frequent chromosomal problems to develop and can be a cause for a small percentage of recurrent miscarriage.
1. Karyotype for genetic translocation: A test for the parents to see if there is a translocation causing recurrent chromosomal problems.
2. Other tests can performed during pregnancy, either in utero on placenta or umbilical (CVS), or amniotic fluid (amniocentesis) or after a miscarriage by collecting and testing the fetal tissue.
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My hope is that this list will not cause fear, because while many things can go wrong, most pregnancies will be succesful. However, if you're suffering from infertility or recurrent miscarriages, it's important to know that many tests are available to you so that you can be empowered to take the necessary steps to achieve a succesful pregnancy.
Friday, February 12, 2010
What to Do When Your Friend or Family Member Miscarries

Friday, January 29, 2010
Healing After a Miscarriage
